|Application ||WB, IHC-P, E|
|Predicted||Human, Rabbit, Monkey, Pig, Goat, Xenopus, Bovine, Guinea Pig|
|Calculated MW||81890 Da|
|Dilution||ELISA (1:128000), IHC-P (5 µg/ml), WB (0.3 - 1 µg/ml)|
|Other Names||CAPN1, Calpain i, Calpain mu-type, Calpain, large polypeptide L1, Calpain-1 catalytic subunit, Calpain 1, Calpain-1 large subunit, CANP, CANP1, Mu CANP, Mu-calpain, Mu-type calpain, MuCANP, Micromolar-calpain, MuCL, CANP 1, CANPL1|
|Target/Specificity||Human CAPN1 / Calpain 1. Reported variants represent identical protein: NP_001185797.1, NP_005177.2, NP_001185798.1.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-CAPN1 / Calpain 1 Antibody (aa468-481) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.|
|Cellular Location||Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding. In granular keratinocytes and in lower corneocytes, colocalizes with FLG and FLG2 (PubMed:21531719).|
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