|Application ||WB, IHC-P, E|
|Calculated MW||97072 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB|
|Other Names||TTK, Cancer/testis antigen 96, ESK, Esk1, MPS1, MPS1L1, Protein kinase esk, PYT, TTK protein kinase, CT96, Monopolar spindle 1-like 1|
|Target/Specificity||Human MPS1 / TTK|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-MPS1 / TTK Antibody (clone 3G7) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.|
|Tissue Location||Present in rapidly proliferating cell lines.|
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