|Application ||WB, IHC-P, E|
|Calculated MW||38499 Da|
|Dilution||ELISA (1:64000), IHC-P (5 µg/ml), WB (0.3 - 1 µg/ml)|
|Other Names||CAPG, AFCP, Actin-regulatory protein CAP-G, Actin regulatory protein CAP-G, Gelsolin-like capping protein, MCP, Macrophage capping protein, Macrophage-capping protein|
|Target/Specificity||Human CAPG / MCP. This antibody is expected to recognize both reported isoforms (NP_001738.2; NP_001243069.1). Reported variants represent identical protein: NP_001243068.1, NP_001738.2.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-CAPG Antibody (aa147-159) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.|
|Cellular Location||Cytoplasm. Nucleus. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
|Tissue Location||Macrophages and macrophage-like cells.|
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