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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-CAPG Antibody (aa147-159)
Anti-CAPG Antibody (aa147-159)
Goat Anti Human Polyclonal Antibody
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- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P40121 |
| Predicted | Human, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 38499 Da |
| Dilution | ELISA (1:64000), IHC-P (5 µg/ml), WB (0.3 - 1 µg/ml) |
| Gene ID | 822 |
|---|---|
| Alias Symbol | CAPG |
| Other Names | CAPG, AFCP, Actin-regulatory protein CAP-G, Actin regulatory protein CAP-G, Gelsolin-like capping protein, MCP, Macrophage capping protein, Macrophage-capping protein |
| Target/Specificity | Human CAPG / MCP. This antibody is expected to recognize both reported isoforms (NP_001738.2; NP_001243069.1). Reported variants represent identical protein: NP_001243068.1, NP_001738.2. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-CAPG Antibody (aa147-159) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CAPG |
|---|---|
| Synonyms | AFCP, MCP |
| Function | Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. |
| Cellular Location | Nucleus. Cytoplasm Melanosome. Cell projection, lamellipodium {ECO:0000250|UniProtKB:P24452}. Cell projection, ruffle {ECO:0000250|UniProtKB:P24452}. Note=In macrophages, may be predominantly cytoplasmic. Nuclear localization was observed in fibroblasts. In macrophages, present at the membrane-cytoplasm interface. In activated macrophages, concentrated in the ruffles of the leading lamellipodia. {ECO:0000250|UniProtKB:P24452} |
| Tissue Location | Macrophages and macrophage-like cells. |
Research Areas
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