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Anti-NUDC Antibody (aa282-331)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9Y266
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 38243 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 10726
Alias Symbol NUDC
Other Names NUDC, HNUDC, MNUDC, NPD011, Nuclear migration protein nudC
Target/Specificity NudC Antibody detects endogenous levels of total NudC protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-NUDC Antibody (aa282-331) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NUDC
Function Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (PubMed:12852857, PubMed:12679384, PubMed:25789526). Necessary for cytokinesis and cell proliferation (PubMed:12852857, PubMed:12679384).
Cellular Location Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody Note=In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern. Localizes to the mitotic spindle in a EML4-dependent manner (PubMed:25789526).
Tissue Location Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart
Research Areas
Citations (0)
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Discontinued
Cat# ALS17941
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