Anti-NUDC Antibody (aa282-331)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9Y266 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 38243 Da |
Dilution | ELISA, IHC-P (1:50), WB |
Gene ID | 10726 |
---|---|
Alias Symbol | NUDC |
Other Names | NUDC, HNUDC, MNUDC, NPD011, Nuclear migration protein nudC |
Target/Specificity | NudC Antibody detects endogenous levels of total NudC protein. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-NUDC Antibody (aa282-331) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NUDC |
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Function | Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (PubMed:12852857, PubMed:12679384, PubMed:25789526). Necessary for cytokinesis and cell proliferation (PubMed:12852857, PubMed:12679384). |
Cellular Location | Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody Note=In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern. Localizes to the mitotic spindle in a EML4-dependent manner (PubMed:25789526). |
Tissue Location | Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart |
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