|Application ||WB, IHC-P, E|
|Predicted||Human, Mouse, Rat|
|Calculated MW||38243 Da|
|Dilution||ELISA, IHC-P (1:50), WB|
|Other Names||NUDC, HNUDC, MNUDC, NPD011, Nuclear migration protein nudC|
|Target/Specificity||NudC Antibody detects endogenous levels of total NudC protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-NUDC Antibody (aa282-331) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.|
|Cellular Location||Cytoplasm, cytoskeleton. Nucleus. Note=In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern|
|Tissue Location||Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.|
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