|Application ||IHC-P, IF, E|
|Calculated MW||113270 Da|
|Dilution||ELISA, IF, IHC-P (1:50)|
|Other Names||CARD14, BIMP2, Card-maguk protein 2, Carma 2, PrP, PSORS2, PSS1, CARMA2|
|Target/Specificity||CAR14 Antibody detects endogenous levels of total CAR14 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-CARD14 Antibody (aa291-340) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.|
|Cellular Location||Isoform 1: Cytoplasm. Isoform 3: Cytoplasm.|
|Tissue Location||Isoform 1 is detected in placenta and epidermal keratinocytes. Isoform 2 is detected in leukocytes and fetal brain.|
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