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Anti-VOPP1 / ECOP Antibody

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q96AW1
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 19224 Da
Dilution ELISA, IHC-P (20 µg/ml), WB
Additional Information
Gene ID 81552
Alias Symbol VOPP1
Other Names VOPP1, ECOP, GASP
Target/Specificity Human VOPP1 / ECOP
Reconstitution & Storage Caprylic acid and ammonium sulfate precipitation
PrecautionsAnti-VOPP1 / ECOP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VOPP1 (HGNC:34518)
Synonyms ECOP, GASP
Function Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed (PubMed:15735698). May sequester WWOX in lysosomal vesicles and thereby regulate WWOX role as tumor suppressor (PubMed:30285739).
Cellular Location Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein. Note=When overexpressed, localizes in the nucleus and perinuclear regions.
Tissue Location Widely expressed with highest levels in thymus and ovary.
Research Areas
Citations (0)
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Discontinued
Cat# ALS17963
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