Anti-VOPP1 / ECOP Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q96AW1 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 19224 Da |
Dilution | ELISA, IHC-P (20 µg/ml), WB |
Gene ID | 81552 |
---|---|
Alias Symbol | VOPP1 |
Other Names | VOPP1, ECOP, GASP |
Target/Specificity | Human VOPP1 / ECOP |
Reconstitution & Storage | Caprylic acid and ammonium sulfate precipitation |
Precautions | Anti-VOPP1 / ECOP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | VOPP1 (HGNC:34518) |
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Synonyms | ECOP, GASP |
Function | Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed (PubMed:15735698). May sequester WWOX in lysosomal vesicles and thereby regulate WWOX role as tumor suppressor (PubMed:30285739). |
Cellular Location | Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein. Note=When overexpressed, localizes in the nucleus and perinuclear regions. |
Tissue Location | Widely expressed with highest levels in thymus and ovary. |
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