|Application ||IHC-P, E|
|Predicted||Human, Mouse, Rat|
|Calculated MW||54546 Da|
|Dilution||ELISA, IHC-P (1:50)|
|Other Names||CHRNA1, Achr-1, AChR-alpha1, ACHRD, CHNRA, ACHRA, FCCMS, SCCMS, CHRNA, CMS2A, NAChR alpha 1|
|Target/Specificity||AChR alpha 1 antibody detects endogenous levels of AChR alpha 1.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-CHRNA1 Antibody (aa168-217) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein|
|Tissue Location||Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus|
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