|Application ||WB, IHC-P, E|
|Calculated MW||21656 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB|
|Other Names||KRAS, C-K-RAS, C-Ki-ras, C-Kirsten-ras protein, GTPase KRas, K-ras p21 protein, K-RAS2B, K-RAS2, KRAS2, NS, NS3, K-RAS4A, KRAS1, RASK2, Transforming protein p21, Oncogene KRAS2, K-Ras 2, K-RAS2A, K-RAS4B, KI-RAS, PR310 c-K-ras oncogene|
|Reconstitution & Storage||Caprylic acid and ammonium sulfate precipitation|
|Precautions||Anti-KRAS Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol|
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