Anti-CCBL1 Antibody (clone 1B12)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q16773 |
Predicted | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2a,k |
Clone Names | 1B12 |
Calculated MW | 47875 Da |
Dilution | ELISA, IF (10 µg/ml), IHC-P (10 µg/ml), WB |
Gene ID | 883 |
---|---|
Alias Symbol | CCBL1 |
Other Names | CCBL1, Beta-lysase, kidney, KAT1, KATI, Kynurenine aminotransferase I, Kyneurenine aminotransferase, Kynurenic acid transferase 1, GTK, Glutamine transaminase K |
Target/Specificity | Human CCBL1 / KAT1 |
Reconstitution & Storage | Protein A purified |
Precautions | Anti-CCBL1 Antibody (clone 1B12) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KYAT1 (HGNC:1564) |
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Synonyms | CCBL1 |
Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others (PubMed:19338303, PubMed:28097769). Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites (PubMed:7883047). Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (PubMed:7883047). |
Cellular Location | Cytoplasm, cytosol. |
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