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Anti-WTAP Antibody (clone 1B11)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15007
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a,k
Clone Names 1B11
Calculated MW 44244 Da
Dilution ELISA, IHC-P (3 - 10 µg/ml), WB
Additional Information
Gene ID 9589
Alias Symbol WTAP
Other Names WTAP, HFL(2)D, KIAA0105, PNAS-132, WT1-associated protein, Female-lethal(2)D homolog
Target/Specificity Human WTAP
Reconstitution & Storage Protein A purified
PrecautionsAnti-WTAP Antibody (clone 1B11) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0105
Function Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).
Cellular Location Nucleus, nucleoplasm Nucleus speckle
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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$ 450.00
Cat# ALS17991
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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