|Application ||WB, IHC-P, E|
|Calculated MW||593389 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB|
|Other Names||KMT2D, AAD10, ALL1-related protein, KABUK1, KMS, Lysine N-methyltransferase 2D, MLL2, Kabuki make-up syndrome, ALR, CAGL114, KMT2B, Lysine N-methyltransferase 2B, TNRC21|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-KMT2D / MLL2 Antibody (clone 2E1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ALR, MLL2, MLL4|
|Function||Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.|
|Tissue Location||Expressed in most adult tissues, including a variety of hematoipoietic cells, with the exception of the liver|
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