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Anti-BCL2 / Bcl-2 Antibody (C-Terminus)

Rabbit Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10415
Predicted Human, Mouse, Rat, Monkey, Bovine
Host Rabbit
Clonality Monoclonal
Isotype IgG
Calculated MW 26266 Da
Dilution ELISA, IHC-P (1:100), IP (1:200), WB (1:1000)
Additional Information
Gene ID 596
Alias Symbol BCL2
Other Names BCL2, Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50
Target/Specificity Detects endogenous levels of total human Bcl-2 protein at 26kD. This antibody does not cross-react with other Bcl-2 family members. Species cross-reactivity: mouse, rat. Species sequence homology: monkey and bovine. Antibody fails in chicken despite ...
Reconstitution & Storage Tissue culture supernatant
PrecautionsAnti-BCL2 / Bcl-2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCL2
Function Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Cellular Location Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Expressed in a variety of tissues.
Research Areas
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$ 450.00
Cat# ALS18001
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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