|Application ||WB, IHC-P, ICC|
|Calculated MW||67931 Da|
|Dilution||ICC, IHC-P (1 - 10 µg/ml), WB (1 µg/ml)|
|Other Names||GBP1, GBP-1, GTP-binding protein 1, Guanylate binding protein 1, HuGBP-1|
|Reconstitution & Storage||Protein G purified|
|Precautions||Anti-GBP1 Antibody (clone 1B1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.|
|Cellular Location||Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.