|Application ||WB, IHC-P, ICC|
|Calculated MW||67931 Da|
|Dilution||ICC, IHC-P (1 - 10 µg/ml), WB (1 µg/ml)|
|Other Names||GBP1, GBP-1, GTP-binding protein 1, Guanylate binding protein 1, HuGBP-1|
|Reconstitution & Storage||Protein G purified|
|Precautions||Anti-GBP1 Antibody (clone 1B1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.|
|Cellular Location||Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor|
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