|Application ||WB, IHC-P, ICC|
|Calculated MW||67931 Da|
|Dilution||ICC, IHC-P (1 - 10 µg/ml), WB (1 µg/ml)|
|Other Names||GBP1, GBP-1, GTP-binding protein 1, Guanylate binding protein 1, HuGBP-1|
|Reconstitution & Storage||Protein G purified|
|Precautions||Anti-GBP1 Antibody (clone 1B1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.|
|Cellular Location||Cytoplasm. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cell membrane. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of IFNG induction. Golgi membrane localization requires isoprenylation and the presence of another IFNG-induced factor|
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