Anti-MLC2 / MYL9 Antibody (aa3-52)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | P24844 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 19827 Da |
Dilution | ELISA, IF, IHC-P (1:50), WB |
Gene ID | 10398 |
---|---|
Alias Symbol | MYL9 |
Other Names | MYL9, 20 kDa myosin light chain, LC20, MLC-2C, MLC2, Myosin RLC, MRLC1, MYRL2 |
Target/Specificity | MRLC2 (Ab-18) Antibody detects endogenous levels of total MRLC2 protein. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-MLC2 / MYL9 Antibody (aa3-52) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MYL9 |
---|---|
Synonyms | MLC2, MRLC1, MYRL2 |
Function | Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (PubMed:11942626, PubMed:2526655). In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9CQ19}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q9CQ19}. Note=Colocalizes with F-actin, MYH9 and PIEZO1 at the actomyosin cortex in myoblasts {ECO:0000250|UniProtKB:Q9CQ19} |
Tissue Location | Smooth muscle tissues and in some, but not all, nonmuscle cells. |
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