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Anti-NFKBIA / IKB Alpha / IKBA Antibody (aa9-58)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25963
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 35609 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 4792
Alias Symbol NFKBIA
Other Names NFKBIA, IkB-alpha, IKBA, IkappaBalpha, MAD3, NF-kappa-B inhibitor alpha, NFKBI, I-kappa-B-alpha, IKB Alpha, MAD-3
Target/Specificity IkappaB-alpha (Ab-42) Antibody detects endogenous levels of total IkappaB-alpha protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-NFKBIA / IKB Alpha / IKBA Antibody (aa9-58) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms IKBA, MAD3, NFKBI
Function Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Cellular Location Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Research Areas
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$ 450.00
Cat# ALS18019
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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