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Anti-PLA2G3 Antibody (Internal)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NZ20
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 57167 Da
Dilution IHC-P (10 µg/ml), WB (1:500 - 1:3000)
Additional Information
Gene ID 50487
Alias Symbol PLA2G3
Other Names PLA2G3, GIII-SPLA2, Phospholipase A2, group III, SPLA2-III, GIII sPLA2, SPLA2III
Target/Specificity Human PLA2G3
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-PLA2G3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLA2G3
Function PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Shows an 11-fold preference for phosphatidylglycerol over phosphatidylcholine (PC). Preferential cleavage: 1-palmitoyl-2-linoleoyl- phosphatidylethanolamine (PE) > 1-palmitoyl-2-linoleoyl-PC > 1- palmitoyl-2-arachidonoyl-PC > 1-palmitoyl-2-arachidonoyl-PE. Plays a role in ciliogenesis.
Cellular Location Secreted. Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
Tissue Location Expressed in kidney, heart, liver, and skeletal muscle. Also present in placenta and peripheral blood leukocytes. Not detected in brain, colon, thymus, spleen and small intestine. In lung, expressed in bronchial epithelial cells and alveolar macrophages, but scarcely detected in alveolar epithelium, arterial walls and interstitial fibroblasts (at protein level). In joints of osteoarthritis and rheumatoid arthritis, expressed in endothelial cells (at protein level). In normal heart, detected in some vessels. In myocardial tissues with acute infarction, expressed in vascular endothelial cells adjacent to cardiomyocytes and those in lesions with granulation Expression in cardiomyocytes is scarce (at protein level). In uterus, breast and colon cancers, detected in tumor cells and neighboring microvascular endothelium, but not in normal glandular tissues (at protein level).
Research Areas
Citations (0)

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$ 395.00
Cat# ALS18037
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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