|Application ||WB, IHC-P, E|
|Calculated MW||58068 Da|
|Dilution||ELISA, IHC-P (1:50), WB|
|Other Names||CYP8B1, CYP12, Cytochrome P450 8B1, CP8B, Sterol 12-alpha-hydroxylase, Sterol 12alpha-hydroxylase, CYPVIIIB1|
|Target/Specificity||Cytochrome P450 8B1 antibody detects endogenous levels of Cytochrome P450 8B1.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-CYP8B1 Antibody (aa357-406) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha- hydroxylated C27 steroids.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein|
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