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Anti-IGFBP3 Antibody (aa130-179)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P17936
Predicted Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 31674 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 3486
Alias Symbol IGFBP3
Other Names IGFBP3, Binding protein 29, Binding protein 53, BP-53, IGF-binding protein 3, IGFBP-3, IBP-3, IBP3
Target/Specificity IGFBP-3 antibody detects endogenous levels of IGFBP-3.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-IGFBP3 Antibody (aa130-179) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGFBP3
Synonyms IBP3
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity (PubMed:19623253). Promotes testicular germ cell apoptosis (PubMed:19952275).
Cellular Location Secreted.
Tissue Location Expressed by most tissues. Present in plasma.
Research Areas
Citations (0)
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$ 555.50
Cat# ALS18048
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