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Anti-PRKX Antibody (aa249-298)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P51817
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 40896 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 5613
Alias Symbol PRKX
Other Names PRKX, Pkare, Protein kinase, X-linked, Protein kinase X-linked, Protein kinase PKX1, Protein kinase X, PKX1
Target/Specificity PRKX Antibodyantibody detects endogenous levels of PRKX.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-PRKX Antibody (aa249-298) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRKX
Synonyms PKX1
Function Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular- like structure formation.
Cellular Location Cytoplasm. Nucleus. Note=cAMP induces nuclear translocation
Tissue Location Widely expressed (at protein level). Specifically expressed in blood by macrophages and granulocytes according to PubMed:9860982.
Research Areas
Citations (0)
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Discontinued
Cat# ALS18050
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