|Application ||WB, IHC-P, E|
|Predicted||Human, Mouse, Rat|
|Calculated MW||54284 Da|
|Dilution||ELISA, IHC-P (1:50), WB|
|Other Names||WASF2, DJ393P12.2, IMD2, Protein WAVE-2, WASF4, WAVE2, SCAR2, WASP family protein member 2, WASP family protein member 4, WAS protein family, member 2|
|Target/Specificity||WASF2 Antibodyantibody detects endogenous levels of WASF2.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-WASF2 / SCAR2 Antibody (aa125-174) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note=At the interface between the lamellipodial actin meshwork and the membrane|
|Tissue Location||Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.|
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