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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-EIF4EBP1 / 4EBP1 Antibody (aa35-84)
Anti-EIF4EBP1 / 4EBP1 Antibody (aa35-84)
Rabbit Anti Mouse Polyclonal Antibody
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Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q13541 |
| Predicted | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 12580 Da |
| Dilution | ELISA, IHC-P (1:50), WB |
| Gene ID | 1978 |
|---|---|
| Alias Symbol | EIF4EBP1 |
| Other Names | EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I, EIF4E-binding protein 1 |
| Target/Specificity | 4E-BP1 Antibody detects endogenous levels of total 4E-BP1 protein. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-EIF4EBP1 / 4EBP1 Antibody (aa35-84) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EIF4EBP1 |
|---|---|
| Function | Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. |
| Cellular Location | Cytoplasm. Nucleus. Note=Localization to the nucleus is unaffected by phosphorylation status. {ECO:0000250|UniProtKB:Q60876} |
Research Areas
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Application Protocols
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$ 555.50
Cat# ALS18068
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