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Anti-MRPL41 / PIG3 / BMRP Antibody (aa81-130)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q8IXM3
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 15383 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 64975
Alias Symbol MRPL41
Other Names MRPL41, BMRP, L41mt, MRP-L41, PIG3, MRP-L27, MRP-L27 homolog, Proliferation-inducing gene 3, RPML27
Target/Specificity MRPL41 Antibody detects endogenous levels of total MRPL41 protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-MRPL41 / PIG3 / BMRP Antibody (aa81-130) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MRPL41
Synonyms BMRP, MRPL27, RPML27
Function Component of the mitochondrial ribosome large subunit (PubMed:28892042, PubMed:25838379, PubMed:25278503). Also involved in apoptosis and cell cycle (PubMed:16024796, PubMed:16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PubMed:16024796).
Cellular Location Mitochondrion
Tissue Location Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level)
Research Areas
Citations (0)
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Discontinued
Cat# ALS18075
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