|Application ||WB, IHC-P, E|
|Predicted||Human, Mouse, Rat|
|Calculated MW||32401 Da|
|Dilution||ELISA, IHC-P (1:50), WB|
|Other Names||HSD11B1, 11-beta-HSD1, 11-DH, CORTRD2, HSD11B, HSD11L, SDR26C1, HDL, HSD11|
|Target/Specificity||HSD11B1 Antibody detects endogenous levels of HSD11B1.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-HSD11B1 / HSD11B Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||HSD11, HSD11L, SDR26C1|
|Function||Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type II membrane protein|
|Tissue Location||Widely expressed. Highest expression in liver.|
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