|Application ||WB, IHC-P, E|
|Calculated MW||116038 Da|
|Dilution||ELISA, IHC-P (1:50), WB|
|Other Names||ITGAV, CD51, CD51 antigen, Integrin, alpha V, MSK8, Integrin Alpha V, Integrin alpha-V, VNRA, Vitronectin receptor, Integrin alphaVbeta3, VTNR|
|Target/Specificity||Integrin alpha V antibody detects endogenous levels of Integrin alpha V.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-ITGAV/Integrin Alpha V/CD51 Antibody (aa755-804) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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