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Anti-RPSA / Laminin Receptor Antibody (aa166-215)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P08865
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 32854 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 3921
Alias Symbol RPSA
Other Names RPSA, 37 kDa laminin receptor, 37LRP, 40S ribosomal protein SA, 67LR, 67 kDa laminin receptor, 37/67 kDa laminin receptor, 67kD, ribosomal protein SA, LAMR1, LAMBR, Laminin receptor 1, LamR, NEM/1CHD4, SA, LRP/LR, Laminin binding protein, Laminin Rec ...
Target/Specificity Laminin-R antibody detects endogenous levels of Laminin-R.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-RPSA / Laminin Receptor Antibody (aa166-215) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPSA {ECO:0000255|HAMAP-Rule:MF_03016}
Synonyms LAMBR, LAMR1
Function Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA.
Cellular Location Cell membrane. Cytoplasm. Nucleus {ECO:0000255|HAMAP-Rule:MF_03016}. Note=67LR is found at the surface of the plasma membrane, with its C-terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus (By similarity) Colocalizes with PPP1R16B in the cell membrane. {ECO:0000255|HAMAP- Rule:MF_03016}
Research Areas
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Discontinued
Cat# ALS18097
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