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Anti-KCNMB4 Antibody (aa70-119)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q86W47
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 23949 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 27345
Alias Symbol KCNMB4
Other Names KCNMB4, BK beta 4, BK channel subunit beta-4, BKbeta4, Hbeta4, K(VCA)beta-4, Slowpoke beta 4, Maxi K channel subunit beta-4, Maxi K beta 4, Slo-beta-4
Target/Specificity MaxiK beta antibody detects endogenous levels of MaxiK beta.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-KCNMB4 Antibody (aa70-119) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNMB4
Function Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Predominantly expressed in brain. In brain, it is expressed in the cerebellum, cerebral cortex, medulla, spinal cord, occipital pole, frontal lobe, temporal lobe, putamen, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus Weakly or not expressed in other tissues.
Research Areas
Citations (0)
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$ 555.50
Cat# ALS18099
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