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Anti-SCN2A / Nav1.2 Antibody (aa983-1032)
Rabbit Anti Human Polyclonal Antibody
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Application 
| IHC-P, E |
|---|---|
| Primary Accession | Q99250 |
| Predicted | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 227975 Da |
| Dilution | ELISA, IHC-P (1:50) |
| Gene ID | 6326 |
|---|---|
| Alias Symbol | SCN2A |
| Other Names | SCN2A, Brain sodium channel type II, BFIC3, BFNIS, EIEE11, HBSC II, HBSCI, Na(v)1.2, NachII, SCN2A2, ScpII, BFIS3, HBA, HBSCII, NAC2, Nav1.2, RNSCPIIR, SCN2A1 |
| Target/Specificity | SCN2A antibody detects endogenous levels of SCN2A. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-SCN2A / Nav1.2 Antibody (aa983-1032) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SCN2A (HGNC:10588) |
|---|---|
| Function | Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:1325650, PubMed:17021166, PubMed:28256214, PubMed:29844171). Implicated in the regulation of hippocampal replay occurring within sharp wave ripples (SPW-R) important for memory (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
Research Areas
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