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Anti-CAMKK2 Antibody (aa374-423)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q96RR4
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 64746 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 10645
Alias Symbol CAMKK2
Other Names CAMKK2, CaM-kinase kinase 2, CaMKK beta, CAMKKB, CaM-KK beta, CaMKK, CAMKK beta protein, CaMKK 2, CaMKKbeta, KIAA0787, CaM KKB, CaM-kinase kinase beta, CaM-KK 2
Target/Specificity CAMKK2 antibody detects endogenous levels of CAMKK2.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-CAMKK2 Antibody (aa374-423) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAMKK2
Synonyms CAMKKB, KIAA0787
Function Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
Cellular Location Nucleus. Cytoplasm. Cell projection, neuron projection. Note=Predominantly nuclear in unstimulated cells, relocalizes into cytoplasm and neurites after forskolin induction.
Tissue Location Ubiquitously expressed with higher levels in the brain. Intermediate levels are detected in spleen, prostate, thyroid and leukocytes. The lowest level is in lung
Research Areas
Citations (0)
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Discontinued
Cat# ALS18112
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