|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||18385 Da|
|Dilution||IHC-P (1:200), WB (1:500 - 1:1000)|
|Other Names||RNASE3, ECP, Ribonuclease 3, RNase 3, Cytotoxic ribonuclease, Eosinophil cationic protein, RNS3|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-RNASE3 Antibody (aa130-170) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.|
|Cellular Location||Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus|
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