Anti-RNASE3 Antibody (aa130-170)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | P12724 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 18385 Da |
Dilution | IHC-P (1:200), WB (1:500 - 1:1000) |
Gene ID | 6037 |
---|---|
Alias Symbol | RNASE3 |
Other Names | RNASE3, ECP, Ribonuclease 3, RNase 3, Cytotoxic ribonuclease, Eosinophil cationic protein, RNS3 |
Target/Specificity | Human RNASE3 |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-RNASE3 Antibody (aa130-170) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RNASE3 |
---|---|
Synonyms | ECP, RNS3 |
Function | Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. |
Cellular Location | Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus |
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