|Application ||WB, IHC-P, E|
|Calculated MW||62304 Da|
|Dilution||ELISA (1:20000 - 1:80000), IHC-P (5 µg/ml), WB (1:500 - 1:1000)|
|Other Names||IL18R1, CD218a antigen, CDw218a, CD218a, IL-1Rrp, IL1 receptor-related protein, IL18RA, Interleukin-18 receptor 1, IL1RRP, IL-18R-1, Cytokine receptor, IL-18R1, IL1R-rp, Interleukin 18 receptor 1|
|Target/Specificity||Human CDw218a / IL18R1.|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-CDw218a / IL18R1 Antibody (aa32-329) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Within the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B (Probable) (PubMed:8626725). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity).|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Highly expressed in leukocytes, spleen, lung. Also expressed, but at lower levels, in liver, small intestine, colon, prostate, thymus, placenta, and heart|
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