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Anti-GTF2I / TFII I Antibody (clone 3E2)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78347
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a,k
Clone Names 3E2
Calculated MW 112416 Da
Dilution ELISA, IF (10 µg/ml), IHC-P (3 - 10 µg/ml), WB
Additional Information
Gene ID 2969
Alias Symbol GTF2I
Other Names GTF2I, BAP-135, BAP135, BTK-associated protein, 135kD, BTK-associated protein 135, DIWS, IB291, SRF-Phox1-interacting protein, WBSCR6, TFII I, TFII-I, BTKAP1, WBS, GTFII-I, SPIN
Target/Specificity Human GTF2I
Reconstitution & Storage Protein A purified
PrecautionsAnti-GTF2I / TFII I Antibody (clone 3E2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GTF2I
Synonyms BAP135, WBSCR6
Function Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C- FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.
Cellular Location Cytoplasm. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00484, ECO:0000269|PubMed:10373551}. Note=Colocalizes with BTK in the cytoplasm
Tissue Location Ubiquitous. Isoform 1 is strongly expressed in fetal brain, weakly in adult brain, muscle, and lymphoblasts and is almost undetectable in other adult tissues, while the other isoforms are equally expressed in all adult tissues
Research Areas
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$ 450.00
Cat# ALS18133
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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