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Anti-CSNK1E / CK1 Epsilon Antibody (clone 2E1)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IF, E
Primary Accession P49674
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a,k
Clone Names 2E1
Calculated MW 47315 Da
Dilution ELISA, IF (10 µg/ml), IHC-P (10 µg/ml)
Additional Information
Gene ID 102800317;1454
Alias Symbol CSNK1E
Other Names CSNK1E, Casein kinase 1 epsilon, Casein kinase i epsilon, CK1 epsilon, CKIE, CKIepsilon, CKI-epsilon, HCKIE, Casein kinase 1, epsilon
Target/Specificity Human CSNK1E / CK1 Epsilon
Reconstitution & Storage Protein A purified
PrecautionsAnti-CSNK1E / CK1 Epsilon Antibody (clone 2E1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSNK1E
Function Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (Probable). Participates in Wnt signaling (PubMed:12556519, PubMed:23413191). Phosphorylates DVL1 (PubMed:12556519). Phosphorylates DVL2 (PubMed:23413191). Phosphorylates NEDD9/HEF1 (By similarity). Central component of the circadian clock (PubMed:16790549). In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation (PubMed:15917222, PubMed:16790549). Controls PER1 and PER2 nuclear transport and degradation (By similarity). Inhibits cytokine-induced granuloytic differentiation (PubMed:15070676).
Cellular Location Cytoplasm. Nucleus.
Tissue Location Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle Expressed in monocytes and lymphocytes but not in granulocytes
Research Areas
Citations (0)
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Discontinued
Cat# ALS18134
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