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Anti-ADCY1 / Adenylate Cyclase 1 Antibody (aa230-280)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q08828
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 123440 Da
Dilution IHC-P (1:200), WB (1:500 - 1:1000)
Additional Information
Gene ID 107
Alias Symbol ADCY1
Other Names ADCY1, 3, 5-cyclic AMP synthetase, Adenylate cyclase type I, AC1, Adenylate cyclase type 1, Adenylyl cyclase 1, ATP pyrophosphate-lyase 1, Adenyl cyclase, Adenylate cyclase 1 (brain), Adenylate cyclase, type i, ATP pyrophosphate-lyase
Target/Specificity Human ADCY1
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-ADCY1 / Adenylate Cyclase 1 Antibody (aa230-280) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADCY1
Function Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels (By similarity). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity).
Cellular Location Membrane {ECO:0000250|UniProtKB:P19754}; Multi- pass membrane protein {ECO:0000250|UniProtKB:P19754}. Cell membrane; Multi-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:O88444}. Membrane raft {ECO:0000250|UniProtKB:P19754}. Note=Expressed in the cytoplasm of supporting cells and hair cells of the cochlea vestibule, as well as to the cochlear hair cell nuclei and stereocilia {ECO:0000250|UniProtKB:O88444}
Tissue Location Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699). Brain, retina and adrenal medulla.
Research Areas
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$ 467.50
Cat# ALS18137
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