|Application ||WB, IHC-P, E|
|Calculated MW||24003 Da|
|Dilution||ELISA (1:2000 - 1:5000), IHC-P (15 µg/ml), WB (1:2000 - 1:5000)|
|Other Names||FGF19, Fibroblast growth factor 19, FGF-19|
|Target/Specificity||Recognizes human FGF-19. Detects a band of ~25kDa by Western blot.|
|Reconstitution & Storage||Protein G purified|
|Precautions||Anti-FGF19 Antibody (clone FG369-1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.|
|Tissue Location||Expressed in fetal brain, cartilage, retina, and adult gall bladder.|
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