|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||89278 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:2000)|
|Other Names||ERCC3, BTF2, GTF2H, RAD25, TFIIH p89, TFIIH, XPB, BTF2 p89, XPBC, TFIIH 89 kDa subunit|
|Target/Specificity||Human ERCC3 / XPB|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-ERCC3 / XPB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage.|
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