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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-ALK-6 / BMPR1B Antibody
Anti-ALK-6 / BMPR1B Antibody
Rabbit Anti Human Polyclonal Antibody
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Application 
| WB, IHC-P, IF |
|---|---|
| Primary Accession | O00238 |
| Predicted | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 56930 Da |
| Dilution | IF (1:50 - 1:200), IHC-P (1:100), WB (1:500 - 1:2000) |
| Gene ID | 658 |
|---|---|
| Alias Symbol | BMPR1B |
| Other Names | BMPR1B, Activin receptor-like kinase 6, ALK-6, Bmp receptor 1b, Bmp receptor ib, BMP receptor type IB, CDw293, CFK-43a, BMPR-1B, ALK6, Type IB BMPR, BMP type-1B receptor, BMPR-IB, CDw293 antigen, Type IB BMP receptor |
| Target/Specificity | Human ALK-6 / BMPR1B |
| Reconstitution & Storage | Affinity purified |
| Precautions | Anti-ALK-6 / BMPR1B Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BMPR1B |
|---|---|
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P36898}; Single-pass type I membrane protein |
Research Areas
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