|Application ||WB, IHC-P, IF|
|Calculated MW||56930 Da|
|Dilution||IF (1:50 - 1:200), IHC-P (1:100), WB (1:500 - 1:2000)|
|Other Names||BMPR1B, Activin receptor-like kinase 6, ALK-6, Bmp receptor 1b, Bmp receptor ib, BMP receptor type IB, CDw293, CFK-43a, BMPR-1B, ALK6, Type IB BMPR, BMP type-1B receptor, BMPR-IB, CDw293 antigen, Type IB BMP receptor|
|Target/Specificity||Human ALK-6 / BMPR1B|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-ALK-6 / BMPR1B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction (By similarity).|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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