|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||91197 Da|
|Dilution||IHC-P (1:200), WB (1:500 - 1:2000)|
|Other Names||BCL11A, B-cell CLL/lymphoma 11A, BCL11A-L, BCL11A-XL, BCL11a-M, B-cell lymphoma/leukemia 11A, BCL-11A, BCL11A-S, CTIP1, COUP-TF-interacting protein 1, HBFQTL5, EVI-9, KIAA1809, ZNF856, C2H2-type zinc finger protein, EVI9, Zinc finger protein 856|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-BCL11A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CTIP1, EVI9, KIAA1809, ZNF856|
|Function||Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity).|
|Cellular Location||Cytoplasm. Nucleus. Note=Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles (By similarity).|
|Tissue Location||Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development|
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