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Anti-CAV1 / Caveolin 1 Antibody (C-Terminus)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC
Primary Accession Q03135
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 20472 Da
Dilution ICC (1:100 - 1:500), IF, IHC-P (1:100), WB (1:500 - 1:1000)
Additional Information
Gene ID 857
Alias Symbol CAV1
Other Names CAV1, Caveolin-1, CGL3, CAV, MSTP085, VIP21, BSCL3
Target/Specificity Recognizes endogenous levels of Caveolin 1 protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-CAV1 / Caveolin 1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAV1
Synonyms CAV
Function May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Cellular Location Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein Membrane, caveola; Peripheral membrane protein. Membrane raft Note=Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae
Tissue Location Expressed in muscle and lung, less so in liver, brain and kidney
Research Areas
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$ 395.00
Cat# ALS18190
Size:
Quantity:
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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