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Anti-PSAP / Prosaposin Antibody

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P07602
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 58113 Da
Dilution ELISA, IHC-P (10 µg/ml), WB
Additional Information
Gene ID 5660
Alias Symbol PSAP
Other Names PSAP, Cerebroside sulfate activator, GLBA, Proactivator polypeptide, Prosaposin, SAP1
Target/Specificity Human PSAP / Prosaposin
Reconstitution & Storage Caprylic acid and ammonium sulfate precipitation
PrecautionsAnti-PSAP / Prosaposin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSAP
Synonyms GLBA, SAP1
Function Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin- C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12). Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
Cellular Location Lysosome
Research Areas
Citations (0)
citation

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Discontinued
Cat# ALS18197
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