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Anti-REG3A Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q06141 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 19395 Da |
| Dilution | ELISA, IHC-P (5 µg/ml), WB |
| Gene ID | 5068 |
|---|---|
| Alias Symbol | REG3A |
| Other Names | REG3A, INGAP, HIP, PAP homologous protein, PAP1, REG-III, REG3, PAP-H, Reg III-alpha, REG-3-alpha, Human proislet peptide, PBCGF |
| Target/Specificity | Human REG3A |
| Reconstitution & Storage | Caprylic acid and ammonium sulfate precipitation |
| Precautions | Anti-REG3A Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | REG3A (HGNC:8601) |
|---|---|
| Function | [Regenerating islet-derived protein 3-alpha 15 kDa form]: Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan (PubMed:16931762). Binds membrane phospholipids and kills bacteria by forming a hexameric membrane-permeabilizing oligomeric pore (PubMed:24256734). |
| Cellular Location | Secreted. Note=Found in the apical region of pancreatic acinar cells |
| Tissue Location | Expressed by keratinocytes (PubMed:27830702). Highly expressed in epidermal keratinocytes of psoriasis patients (at protein level) (PubMed:22727489). Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis (PubMed:1469087). |
Research Areas
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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