|Application ||WB, IHC-P, E|
|Calculated MW||18354 Da|
|Dilution||ELISA, IHC-P (5 µg/ml), WB|
|Other Names||RNASE2, EDN, Eosinophil-derived neurotoxin, Ribonuclease US, RNase 2, RNase UpI-2, RNS2, Non-secretory ribonuclease, Ribonuclease 2|
|Target/Specificity||Human RNASE2 / EDN|
|Reconstitution & Storage||Caprylic acid and ammonium sulfate precipitation|
|Precautions||Anti-RNASE2 / EDN Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.|
|Cellular Location||Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule|
|Tissue Location||Liver, lung, spleen, leukocytes and body fluids|
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