|Application ||WB, IHC-P, E|
|Calculated MW||12473 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB|
|Other Names||TCEB1, Elongin 15 kDa subunit, EloC, SIII, SIII p15, Elongin-C|
|Target/Specificity||Human SIII / TCEB1|
|Reconstitution & Storage||Caprylic acid and ammonium sulfate precipitation|
|Precautions||Anti-TCEB1 / Elongin C Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).|
|Tissue Location||Overexpressed in prostate cancer cell line PC- 3 and breast cancer cell line SK-BR-3|
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