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Anti-TIMP1 Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01033
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 23171 Da
Dilution ELISA, IHC-P (10 µg/ml), WB
Additional Information
Gene ID 7076
Alias Symbol TIMP1
Other Names TIMP1, CLGI, EPA, HCI, Metalloproteinase inhibitor 1, TIMP-1, Collagenase inhibitor
Target/Specificity Human TIMP1 / TIMP-1
Reconstitution & Storage Caprylic acid and ammonium sulfate precipitation
PrecautionsAnti-TIMP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIMP1
Synonyms CLGI, TIMP
Function Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
Cellular Location Secreted
Tissue Location Detected in rheumatoid synovial fluid (at protein level).
Research Areas
Citations (0)

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$ 395.00
Cat# ALS18203
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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