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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   Anti-CD79A / CD79 Alpha Antibody (N-Terminus, clone SP18)   

Anti-CD79A / CD79 Alpha Antibody (N-Terminus, clone SP18)

Rabbit Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, Flo
Primary Accession P11912
Predicted Human
Host Rabbit
Clonality Monoclonal
Isotype IgG
Clone Names SP18
Calculated MW 25038 Da
Dilution Flo (1:100), IHC-P (1:100 - 1:400)
Additional Information
Gene ID 973
Alias Symbol CD79A
Other Names CD79A, CD79a antigen, Ig-alpha, MB-1, MB-1 membrane glycoprotein, Surface IgM-associated protein, MB1
Target/Specificity Human CD79A
Reconstitution & Storage Tissue culture supernatant
PrecautionsAnti-CD79A / CD79 Alpha Antibody (N-Terminus, clone SP18) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD79A
Synonyms IGA, MB1
Function Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src- family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Tissue Location B-cells.
Research Areas
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$ 395.00
Cat# ALS18227
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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