Anti-CXCL4 / PF4 Antibody (clone RTO)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P02776 |
Predicted | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2b |
Clone Names | RTO |
Calculated MW | 10845 Da |
Dilution | ELISA, IHC-P (10 µg/ml), WB |
Gene ID | 5196 |
---|---|
Alias Symbol | PF4 |
Other Names | PF4, C-X-C motif chemokine 4, CXCL4, Iroplact, Oncostatin-A, PF-4, SCYB4, Platelet factor 4 |
Target/Specificity | This antibody is specific for Human Platelet Factor IV. Clone RTO is seen to bind free PF4 in the absence of any bound heparin. |
Reconstitution & Storage | Protein G purified |
Precautions | Anti-CXCL4 / PF4 Antibody (clone RTO) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PF4 |
---|---|
Synonyms | CXCL4, SCYB4 |
Function | Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. |
Cellular Location | Secreted. |
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