|Application ||WB, IHC-P, E|
|Calculated MW||10845 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB|
|Other Names||PF4, C-X-C motif chemokine 4, CXCL4, Iroplact, Oncostatin-A, PF-4, SCYB4, Platelet factor 4|
|Target/Specificity||This antibody is specific for Human Platelet Factor IV. Clone RTO is seen to bind free PF4 in the absence of any bound heparin.|
|Reconstitution & Storage||Protein G purified|
|Precautions||Anti-CXCL4 / PF4 Antibody (clone RTO) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.|
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