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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-MLANA / Melan-A Antibody (clone A103)   

Anti-MLANA / Melan-A Antibody (clone A103)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, Flo
Primary Accession Q16655
Predicted Human, Mouse, Rat, Dog
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names A103
Calculated MW 13157 Da
Dilution Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml), IHC-P (0.5 - 5 µg/ml), WB (0.5 - 1 µg/ml)
Additional Information
Gene ID 2315
Alias Symbol MLANA
Other Names MLANA, Antigen LB39-AA, Antigen SK29-AA, Melan-A, Protein Melan-A, MART-1, MART1
Target/Specificity Human MLANA / Melan-A
Reconstitution & Storage Protein G purified
PrecautionsAnti-MLANA / Melan-A Antibody (clone A103) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MART1
Function Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Cellular Location Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation
Tissue Location Expression is restricted to melanoma and melanocyte cell lines and retina
Research Areas
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$ 395.00
Cat# ALS18240
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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