Anti-NKG2DL4 / ULBP4 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q8TD07 |
Predicted | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 30122 Da |
Dilution | ELISA, IHC-P (10 µg/ml), WB (1 - 2 µg/ml) |
Gene ID | 135250 |
---|---|
Alias Symbol | RAET1E |
Other Names | RAET1E, BA350J20.7, LETAL, RAE-1-like transcript 4, RAET1E2, RL-4, N2DL-4, N2DL4, ULBP4, NKG2D ligand 4, NKG2DL4 |
Target/Specificity | RAET1E antibody is human and mouse reactive. At least four isoforms of RAET1E are known to exist; this antibody will detect all four. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-NKG2DL4 / ULBP4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RAET1E {ECO:0000303|PubMed:11827464, ECO:0000312|HGNC:HGNC:16793} |
---|---|
Function | Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. |
Cellular Location | Membrane; Single- pass type I membrane protein |
Tissue Location | Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic acid. |
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