|Application ||WB, IHC-P, E|
|Calculated MW||30122 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB (1 - 2 µg/ml)|
|Other Names||RAET1E, BA350J20.7, LETAL, RAE-1-like transcript 4, RAET1E2, RL-4, N2DL-4, N2DL4, ULBP4, NKG2D ligand 4, NKG2DL4|
|Target/Specificity||RAET1E antibody is human and mouse reactive. At least four isoforms of RAET1E are known to exist; this antibody will detect all four.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-NKG2DL4 / ULBP4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||LETAL, N2DL4, ULBP4|
|Function||Ligand for the KLRK1 receptor. Delivers activating signals to NK cells and promotes tumor immune surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic acid|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.