|Application ||WB, IHC-P, E|
|Predicted||Human, Mouse, Rat|
|Calculated MW||26688 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB (1 - 2 µg/ml)|
|Other Names||VTI1B, Vti1-rp1, VTI2, V-SNARE, VTI1, VTI1-LIKE, VTI1L, VTI1L1|
|Target/Specificity||VTI1b antibody is human, mouse and rat reactive. At least three isoforms of VTI1a are known to exist; this antibody will detect all three isoforms. VTI1b antibody is predicted to not cross-react with VTI1a.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-VTI1B Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||VTI1, VTI1L, VTI1L1, VTI2|
|Function||V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.|
|Cellular Location||Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule|
|Tissue Location||Expressed in all tissues examined.|
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