Anti-JAGN1 Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q8N5M9 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 21125 Da |
Dilution | ELISA, IHC-P (10 µg/ml), WB |
Gene ID | 84522 |
---|---|
Alias Symbol | JAGN1 |
Other Names | JAGN1, Jagunal homolog 1 (Drosophila), GL009, Protein jagunal homolog 1 |
Target/Specificity | JAGN1 antibody is human, mouse and rat reactive. At least four isoforms of JAGN1 are known to exist; this antibody will detect all but isoform 2. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-JAGN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | JAGN1 (HGNC:26926) |
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Function | Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport. Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils. |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
Tissue Location | Ubiquitously expressed. |
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