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Anti-UBAP2L Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, ICC, E |
|---|---|
| Primary Accession | Q14157 |
| Predicted | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 114535 Da |
| Dilution | ELISA, ICC (10 µg/ml), IHC-P (10 µg/ml), WB (1 - 2 µg/ml) |
| Gene ID | 9898 |
|---|---|
| Alias Symbol | UBAP2L |
| Other Names | UBAP2L, NICE-4, KIAA0144, NICE4 |
| Target/Specificity | UBAP2L antibody is human and mouse reactive. At least four isoforms of UBAP2L are known to exist; this antibody will detect all four isoforms. This antibody is predicted to not cross-react with UBAP2. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-UBAP2L Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBAP2L (HGNC:29877) |
|---|---|
| Synonyms | KIAA0144, NICE4 |
| Function | Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage (PubMed:35633597). Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT- HSCs) (By similarity). Required for efficient formation of stress granules (PubMed:29395067). |
| Cellular Location | Nucleus. Chromosome. Cytoplasm Cytoplasm, Stress granule Note=Associates with nuclear chromatin. |
| Tissue Location | Ubiquitous.. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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